Sunday 7 June 2015

New link between genes and transsexualism

The Spanish team of scientists researching gender dysphoria have just published a new find, linking differences in a gene to transsexualism.

The study called The CYP17 MspA1 Polymorphism and the Gender Dysphoria, published in The Journal of Sexual Medicine (2015), was headed by geneticist Rosa Fernández. The studied genetic polymorphism on the CYPA1 gene had been previously linked to higher levels of serum testosterone, progesterone, and estradiol. The find is exciting because hormone levels in the brain have been shown to shape gender identity, linking this genetic polymorphism to a plausible pathway causing transsexualism.

Rosa Fernández has previously published other studies about other genetic links to transsexualism. In 2013, she found that The (CA)n Polymorphism of ERβ Gene is Associated with FtM Transsexualism, whereas the 2014 study Association Study of ERβ, AR, and CYP19A1 Genes and MtF Transsexualism produced negative results.

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